Specification points
Cambridge Cambridge International AS & A Level Biology 9700
323 points in 20 topics, with Cambridge's codes and titles.
Grade boundaries·Cambridge command words
Codes and titles are read by a script from Cambridge's published specification and have not been checked by a person. What each point covers is in the specification itself: Cambridge’s specification.
1 Cell structure
- 1.1 The microscope in cell studies
- 1.1.1 Preparing slides for light microscopy
- 1.1.2 Drawing cells
- 1.1.3 Calculating magnification and actual size
- 1.1.4 Eyepiece graticule and stage micrometer
- 1.1.5 Resolution and magnification
- 1.2 Cells as the basic units of living organisms
- 1.2.1 Eukaryotic organelles and their functions
- 1.2.2 Interpreting images of plant and animal cells
- 1.2.3 Comparing plant and animal cells
- 1.2.4 ATP for energy-requiring processes
- 1.2.5 Structure of prokaryotic cells
- 1.2.6 Comparing prokaryotic and eukaryotic cells
- 1.2.7 Structure of viruses
2 Biological molecules
- 2.1 Testing for biological molecules
- 2.1.1 Biochemical tests
- 2.1.2 Semi-quantitative Benedict's test
- 2.1.3 Test for non-reducing sugars
- 2.2 Carbohydrates and lipids
- 2.2.1 Alpha- and beta-glucose
- 2.2.2 Monomers, polymers and saccharides
- 2.2.3 Covalent bonds in polymers
- 2.2.4 Reducing and non-reducing sugars
- 2.2.5 Forming glycosidic bonds
- 2.2.6 Hydrolysis of glycosidic bonds
- 2.2.7 Starch and glycogen
- 2.2.8 Cellulose and plant cell walls
- 2.2.9 Structure of triglycerides
- 2.2.10 Functions of triglycerides
- 2.2.11 Structure of phospholipids
- 2.3 Proteins
- 2.3.1 Amino acids and peptide bonds
- 2.3.2 Levels of protein structure
- 2.3.3 Bonds in protein shape
- 2.3.4 Globular and fibrous proteins
- 2.3.5 Structure of haemoglobin
- 2.3.6 Haemoglobin structure and function
- 2.3.7 Structure of collagen
- 2.3.8 Collagen structure and function
- 2.4 Water
- 2.4.1 Hydrogen bonding and properties of water
3 Enzymes
- 3.1 Mode of action of enzymes
- 3.1.1 Intracellular and extracellular enzymes
- 3.1.2 Mode of action of enzymes
- 3.1.3 Measuring rates of enzyme reactions
- 3.1.4 Colorimeters for enzyme reactions
- 3.2 Factors that affect enzyme action
- 3.2.1 Factors affecting enzyme activity
- 3.2.2 Vmax and the Michaelis–Menten constant
- 3.2.3 Competitive and non-competitive inhibition
- 3.2.4 Immobilised enzymes
4 Cell membranes and transport
- 4.1 Fluid mosaic membranes
- 4.1.1 Fluid mosaic model
- 4.1.2 Cholesterol, glycolipids and glycoproteins
- 4.1.3 Roles of membrane components
- 4.1.4 Cell signalling
- 4.2 Movement into and out of cells
- 4.2.1 Membrane transport processes
- 4.2.2 Investigating diffusion and osmosis
- 4.2.3 Surface area to volume ratio
- 4.2.4 Surface area to volume ratio and diffusion
- 4.2.5 Estimating water potential of tissues
- 4.2.6 Water potential and plant and animal cells
5 The mitotic cell cycle
- 5.1 Replication and division of nuclei and cells
- 5.1.1 Structure of a chromosome
- 5.1.2 Importance of mitosis
- 5.1.3 The mitotic cell cycle
- 5.1.4 Role of telomeres
- 5.1.5 Stem cells in repair
- 5.1.6 Tumour formation
- 5.2 Chromosome behaviour in mitosis
- 5.2.1 Chromosome behaviour during mitosis
- 5.2.2 Identifying stages of mitosis
6 Nucleic acids and protein synthesis
- 6.1 Structure of nucleic acids and replication of DNA
- 6.1.1 Structure of nucleotides and ATP
- 6.1.2 Purines and pyrimidines
- 6.1.3 Structure of DNA
- 6.1.4 Semi-conservative replication
- 6.1.5 Structure of mRNA
- 6.2 Protein synthesis
- 6.2.1 Genes and polypeptides
- 6.2.2 The universal genetic code
- 6.2.3 Transcription and translation
- 6.2.4 Template and non-transcribed strands
- 6.2.5 RNA splicing
- 6.2.6 Gene mutation
- 6.2.7 Substitution, deletion and insertion mutations
7 Transport in plants
- 7.1 Structure of transport tissues
- 7.1.1 Plan diagrams of stems, roots and leaves
- 7.1.2 Distribution of xylem and phloem
- 7.1.3 Drawing xylem and phloem cells
- 7.1.4 Structure and function of xylem and phloem
- 7.2 Transport mechanisms
- 7.2.1 Transport of dissolved substances in plants
- 7.2.2 Apoplast and symplast pathways
- 7.2.3 Transpiration
- 7.2.4 Cohesion-tension and adhesion
- 7.2.5 Xerophytic leaf adaptations
- 7.2.6 Assimilates moving from sources to sinks
- 7.2.7 Companion cells loading phloem
- 7.2.8 Mass flow in phloem
8 Transport in mammals
- 8.1 The circulatory system
- 8.1.1 Closed double circulation
- 8.1.2 Main blood vessels of pulmonary and systemic circulations
- 8.1.3 Identifying and drawing blood vessels
- 8.1.4 Structure and function of blood vessels
- 8.1.5 Identifying blood cells
- 8.1.6 Water in blood and transport
- 8.1.7 Tissue fluid formation
- 8.2 Transport of oxygen and carbon dioxide
- 8.2.1 Transport of oxygen and carbon dioxide
- 8.2.2 The chloride shift
- 8.2.3 Plasma and carbon dioxide transport
- 8.2.4 Oxygen dissociation curve
- 8.2.5 Importance of the dissociation curve
- 8.2.6 The Bohr shift
- 8.3 The heart
- 8.3.1 Structure of the mammalian heart
- 8.3.2 Thickness of heart chamber walls
- 8.3.3 The cardiac cycle
- 8.3.4 Control of the cardiac cycle
9 Gas exchange
10 Infectious diseases
11 Immunity
- 11.1 The immune system
- 11.1.1 Phagocytes
- 11.1.2 Self and non-self antigens
- 11.1.3 Primary immune response
- 11.1.4 Memory cells and secondary response
- 11.2 Antibodies and vaccination
- 11.2.1 Antibody structure and function
- 11.2.2 Hybridoma method
- 11.2.3 Monoclonal antibodies in diagnosis and treatment
- 11.2.4 Types of immunity
- 11.2.5 Vaccines
- 11.2.6 Vaccination programmes
12 Energy and respiration
- 12.1 Energy
- 12.1.1 Need for energy in organisms
- 12.1.2 ATP as energy currency
- 12.1.3 Synthesis of ATP
- 12.1.4 Energy values of respiratory substrates
- 12.1.5 Respiratory quotient
- 12.1.6 Calculating RQ
- 12.1.7 Measuring RQ with respirometers
- 12.2 Respiration
- 12.2.1 Sites of aerobic respiration stages
- 12.2.2 Glycolysis
- 12.2.3 Pyruvate entering mitochondria
- 12.2.4 The link reaction
- 12.2.5 The Krebs cycle
- 12.2.6 Decarboxylation and dehydrogenation in the Krebs cycle
- 12.2.7 Roles of NAD and FAD
- 12.2.8 Oxidative phosphorylation
- 12.2.9 Structure and function of mitochondria
- 12.2.10 Anaerobic respiration in mammals and yeast
- 12.2.11 Aerobic versus anaerobic energy yield
- 12.2.12 Rice adaptations to flooding
- 12.2.13 Redox indicators and respiration rate
- 12.2.14 Temperature and respiration rate
13 Photosynthesis
- 13.1 Photosynthesis as an energy transfer process
- 13.1.1 Chloroplast structure and function
- 13.1.2 ATP and reduced NADP in the Calvin cycle
- 13.1.3 Sites of photosynthesis stages
- 13.1.4 Chloroplast pigments
- 13.1.5 Absorption and action spectra
- 13.1.6 Chromatography of chloroplast pigments
- 13.1.7 Cyclic and non-cyclic photophosphorylation
- 13.1.8 Cyclic photophosphorylation
- 13.1.9 Non-cyclic photophosphorylation
- 13.1.10 Photophosphorylation and chemiosmosis
- 13.1.11 The Calvin cycle
- 13.1.12 Uses of Calvin cycle intermediates
- 13.2 Investigation of limiting factors
- 13.2.1 Limiting factors of photosynthesis
- 13.2.2 Effects of limiting factors
- 13.2.3 Investigating photosynthesis with redox indicators
- 13.2.4 Investigating photosynthesis in whole plants
14 Homeostasis
- 14.1 Homeostasis in mammals
- 14.1.1 Homeostasis
- 14.1.2 Principles of homeostasis
- 14.1.3 Urea production
- 14.1.4 Structure of the kidney
- 14.1.5 Structure of a nephron
- 14.1.6 Formation of urine
- 14.1.7 Bowman's capsule and proximal tubule
- 14.1.8 Osmoregulation
- 14.1.9 Cell signalling and glucagon
- 14.1.10 Negative feedback and blood glucose
- 14.1.11 Glucose test strips and biosensors
- 14.2 Homeostasis in plants
- 14.2.1 Stomatal responses to conditions
- 14.2.2 Daily rhythms of stomata
- 14.2.3 Guard cells and stomatal opening
- 14.2.4 Abscisic acid and stomatal closure
15 Control and coordination
- 15.1 Control and coordination in mammals
- 15.1.1 Features of the endocrine system
- 15.1.2 Nervous versus endocrine systems
- 15.1.3 Sensory, motor and intermediate neurones
- 15.1.4 Sensory receptor cells
- 15.1.5 Action potential in a taste receptor
- 15.1.6 Resting and action potentials
- 15.1.7 Saltatory conduction
- 15.1.8 Refractory period
- 15.1.9 Cholinergic synapses
- 15.1.10 Stimulating contraction in striated muscle
- 15.1.11 Ultrastructure of striated muscle
- 15.1.12 Sliding filament model
- 15.2 Control and coordination in plants
- 15.2.1 Venus fly trap response
- 15.2.2 Auxin and elongation growth
- 15.2.3 Gibberellin in barley germination
16 Inheritance
- 16.1 Passage of information from parents to offspring
- 16.1.1 Haploid and diploid
- 16.1.2 Homologous chromosomes
- 16.1.3 Need for reduction division
- 16.1.4 Chromosome behaviour during meiosis
- 16.1.5 Identifying stages of meiosis
- 16.1.6 Crossing over and independent assortment
- 16.1.7 Random fertilisation and variation
- 16.2 The roles of genes in determining the phenotype
- 16.2.1 Genetic terminology
- 16.2.2 Monohybrid and dihybrid crosses
- 16.2.3 Autosomal linkage and epistasis
- 16.2.4 Test crosses
- 16.2.5 Chi-squared test
- 16.2.6 Genes, proteins and phenotype
- 16.2.7 Gibberellin and stem elongation genes
- 16.3 Gene control
- 16.3.1 Structural and regulatory genes
- 16.3.2 The lac operon
- 16.3.3 Transcription factors
- 16.3.4 Gibberellin and DELLA proteins
17 Selection and evolution
- 17.1 Variation
- 17.1.1 Genetic and environmental variation
- 17.1.2 Discontinuous and continuous variation
- 17.1.3 Genetic basis of variation
- 17.1.4 The t-test
- 17.2 Natural and artificial selection
- 17.2.1 Natural selection
- 17.2.2 Stabilising, disruptive and directional selection
- 17.2.3 Founder effect and genetic drift
- 17.2.4 Antibiotic resistance as natural selection
- 17.2.5 Hardy–Weinberg principle
- 17.2.6 Selective breeding
- 17.2.7 Examples of selective breeding
- 17.3 Evolution
- 17.3.1 Theory of evolution
- 17.3.2 DNA sequences and evolutionary relationships
- 17.3.3 Allopatric and sympatric speciation
18 Classification, biodiversity and conservation
- 18.1 Classification
- 18.1.1 Species concepts
- 18.1.2 Three domains
- 18.1.3 Archaea versus Bacteria
- 18.1.4 Taxonomic hierarchy
- 18.1.5 Features of the eukaryotic kingdoms
- 18.1.6 Classification of viruses
- 18.2 Biodiversity
- 18.2.1 Ecosystem and niche
- 18.2.2 Levels of biodiversity
- 18.2.3 Random sampling and biodiversity
- 18.2.4 Assessing distribution and abundance
- 18.2.5 Spearman's and Pearson's correlation
- 18.2.6 Simpson's index of diversity
- 18.3 Conservation
- 18.3.1 Causes of extinction
- 18.3.2 Need to maintain biodiversity
- 18.3.3 Zoos, gardens, parks and seed banks
- 18.3.4 Assisted reproduction in conservation
- 18.3.5 Controlling invasive alien species
- 18.3.6 IUCN and CITES
19 Genetic technology
- 19.1 Principles of genetic technology
- 19.1.1 Recombinant DNA
- 19.1.2 Genetic engineering
- 19.1.3 Sources of genes for transfer
- 19.1.4 Enzymes and vectors in gene transfer
- 19.1.5 Transferring promoters
- 19.1.6 Marker genes
- 19.1.7 Gene editing
- 19.1.8 Polymerase chain reaction
- 19.1.9 Gel electrophoresis
- 19.1.10 Microarrays
- 19.1.11 Sequence and structure databases
- 19.2 Genetic technology applied to medicine
- 19.2.1 Recombinant human proteins
- 19.2.2 Genetic screening
- 19.2.3 Gene therapy
- 19.2.4 Ethics of genetic screening and gene therapy
- 19.3 Genetically modified organisms in agriculture
- 19.3.1 Genetic engineering in food production
- 19.3.2 Ethics of GMOs in food